Quinine Sulphate

Tradeasia International Pte. Ltd. established in 2002 and is headquartered in Singapore is a global chemical supplier and trading organization providing integrated chemical procurement services with a level of certainty and trust, which makes Tradeasia stands unique.It was setup with the sole intention of carrying out chemical distribution services especially to commodity industries in many parts of the world.

Quinine Sulphate

Quinine Sulfate is the sulfate salt form of the quinidine alkaloid isolate quinine. Quinine has many mechanisms of action, including reduction of oxygen intake and carbohydrate metabolism; disruption of DNA replication and transcription via DNA intercalation; and reduction of the excitability of muscle fibers via alteration of calcium distribution. This agent also inhibits the drug efflux pump P-glycoprotein which is overexpressed in multi-drug resistant tumors and may improve the efficacy of some antineoplastic agents.

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Product Applications

Quinine sulfate at a dose of 200–300 mg at night has been used for many years to treat nocturnal leg cramps. Usually idiopathic, these muscle cramps are common, particularly in older patients. Quinine may help by decreasing the excitability of the motor end-plate and increasing the muscle refractory period. Quinine sulfate at a dose of 200–300 mg at night has been used for many years to treat nocturnal leg cramps. Usually idiopathic, these muscle cramps are common, particularly in older patients. 

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